Diet Hormones and Atherosclerosis a Review of Research Grants Supported by the National Heart Institute Fiscal Years 1949 1958

DIET AND ATHEROSCLEROSIS It is almost fifty years since Anitschow described
the rapid development of atherosclerosis in rabbits after prolonged cholesterol
feeding . Possibly this date marks the birth of the suspicion that diet may be an ...

Author: National Institutes of Health (U.S.)

Publisher:

ISBN:

Category:

Page: 97

View: 651


Diet Lipid Metabolism and Atherosclerosis

of development of atherosclerosis . Organic peroxides , presumably resulting
from oxidative polymerization , have been identified in atheromas and in serum ;
irradiation of aortic plaques with ultraviolet light gives signals on electron spin ...

Author: National Heart Institute (U.S.)

Publisher:

ISBN:

Category: Arteriosclerosis

Page: 370

View: 526


Diet Hormones and Atherosclerosis

12 In the rabbit , mixed soybean sterols are absorbed , inhibit hepatic synthesis of
cholesterol , 118 and produce aortic atherosclerosis . Efforts are now being made
to separate , purify , and characterize the sitosterols and to compare the ...

Author: National Heart Institute (U.S.). Grants and Training Branch

Publisher:

ISBN:

Category: Arteriosclerosis

Page: 97

View: 519


CBD Oil for Atherosclerosis

Introduction Inflаmmаtіоn is a natural, protective rеѕроnѕе to іnfесtіоn.

Author: Dr James Coker

Publisher:

ISBN: 9781710206746

Category:

Page: 50

View: 347

Introduction Inflаmmаtіоn is a natural, protective rеѕроnѕе to іnfесtіоn. Itѕ рurроѕе іѕ tо rеmоvе раthоgеnѕ оr dаmаgеd tissue, аlthоugh it's very іmроrtаnt thаt thе lосаtіоn оf damage іѕ саrеfullу monitored. If іnflаmmаtіоn реrѕіѕtѕ longer than nееdеd, it can cause hаrm tо the bоdу. Inflаmmаtоrу dіѕеаѕе аthеrоѕсlеrоѕіѕ, аlѕо known as coronary аrtеrу dіѕеаѕе (CAD), іѕ a very common соntrіbutіng factor to life-threatening hеаrt соndіtіоnѕ іnсludіng ѕtrоkеѕ аnd heart attacks. Athеrоѕсlеrоѕіѕ, most often thrоugh thrombosis, lеаdѕ to ischemic hеаrt dіѕеаѕе and іѕсhеmіс ѕtrоkе, thе lеаdіng саuѕеѕ оf death аnd dіѕаbіlіtу worldwide. Advаnсеd аthеrоѕсlеrоѕіѕ аnd іmаgіng оf аthеrоѕсlеrоѕіѕ аrе the fосuѕ оf thіѕ dіѕѕеrtаtіоn wіth particular emphasis on thе vulnerable рlаԛuе аnd vulnerable рlаԛuе detection.

Research Grants Index

... 14734-02 0011 Hormonal factors in atherosclerosis and collagen ( dogst
human ) atherosclerosis - Electrophysiology ... Androsterone and related C19
steroids-M HL - 14138-03 Center for research on atherosclerosis atherosclerotic
hearts ...

Author: National Institutes of Health (U.S.). Division of Research Grants

Publisher:

ISBN:

Category: Medicine

Page:

View: 865


Atherosclerosis

Atherosclerosis is a subject of enormous contention for cardiologists and in general for all medical doctors. With this publication we have given you a concise "state-of-the-art" look at the world of atheroma.

Author: Luigi Gianturco

Publisher: BoD – Books on Demand

ISBN: 178923560X

Category: Medical

Page: 128

View: 898

Atherosclerosis is a subject of enormous contention for cardiologists and in general for all medical doctors. With this publication we have given you a concise "state-of-the-art" look at the world of atheroma. Many other elements could be included and so it is only a brief analysis of "today" (the preventive medicine era) and "tomorrow" (transforming the cure medicine era into the care medicine era) but also remembering "yesterday" (the ex-cathedra medicine era). Let's hope our arteries are free from atherosclerotic events: have a good read!

Subject Index of Current Research Grants and Contracts Administered by the National Heart Lung and Blood Institute

... M POTHL - 13262-03 Arterial wall in atherosclerosis ** P17HL - 14164-05
0021 Arteriosclerosis research center - RO1 HL 14378-04 Lipemias and
reconstructive cardiac ** POTHL - 13262-03 0011 Arterial wall in atherosclerosis
- Resource ...

Author: National Heart, Lung, and Blood Institute

Publisher:

ISBN:

Category: Cardiovascular system

Page:

View: 693


Atherosclerosis

This book highlights advances in atherosclerosis and links these to relevant therapeutic strategies. It compiles and details cutting-edge research in cardiovascular medicine from internationally renowned authors.

Author: Christian Weber

Publisher: CRC Press

ISBN: 9814316261

Category: Medical

Page: 492

View: 942

In recent years, the understanding of the pathophysiological processes of atherosclerosis, a chronic inflammatory disease of the vessel wall being the leading cause for mortality in industrial countries, has tremendously increased. The feasibility of translating such knowledge to novel therapeutic approaches is currently being explored at various levels. This book highlights advances in atherosclerosis and links these to relevant therapeutic strategies. It compiles and details cutting-edge research in cardiovascular medicine from internationally renowned authors.

Atherosclerosis

IS ATHEROSCLEROSIS PREVENTABLE ? 13 life span produces only moderate
atherosclerosis , explains why a similar normocholesterolemic period effects the
regression of lesions . We have no data to indicate the degree of reversibility of ...

Author: Campbell Moses

Publisher:

ISBN:

Category: Arteriosclerosis

Page: 239

View: 535


Atherosclerosis XIII

Hungarian Atherosclerosis Society Indian Society for Atherosclerosis Research
Indonesian Cardiovascular Society ( ICS ) , Council on Atherosclerosis Iranian
Heart Foundation Council on Atherosclerosis , Nutrition & Lipid Research Israel ...

Author: Yūji Matsuzawa

Publisher: Elsevier Science Health Science Division

ISBN: 9780444514486

Category: Medical

Page: 626

View: 480

These proceedings not only summarized the scientific and technological achievements in atherosclerosis research during the 20th century but also include the latest topics for future progress and development in this new millennium, highlighting the recent advances in vascular biology, angiogenesis and atherogenesis, pathogenesis of metabolic syndrome. The articles also encompass vast range of clinical and basic research field of atherosclerosis, including epidemiology, lipoprotein metabolism, pharmacology, clinical trials, nutrition, pathogenesis, diagnosis and prevention as well as its treatment.

Atherosclerosis

With atherosclerosis being the number one cause of death in the western world, this handbook and ready reference provides a comprehensive account of the different stages and factors in the development of the atherosclerotic plaque.

Author: Sarah Jane George

Publisher: John Wiley & Sons

ISBN: 9783527629596

Category: Science

Page: 420

View: 339

With atherosclerosis being the number one cause of death in the western world, this handbook and ready reference provides a comprehensive account of the different stages and factors in the development of the atherosclerotic plaque. Each chapter is written by experts in the field and highlights the role of specific mediators of atherosclerotic plaque development, as well as potential therapeutic targets. A large amount of this up-to-date information is conveyed by way of tables and schematic figures, in a readily comprehensible manner. A must-have for master and PhD students, researchers, MDs and lecturers in vascular biology and cardiology, as well as for academics and scientists in the pharmaceutical industry.

Reversing Atherosclerosis

coronary and aortic atherosclerosis . J Atheroscler Res , 10 : 303 , 1969 . 49 .
Strong , J . P . and Richards , M . L . : Cigarette smoking and atherosclerosis in
autopsied men . Atherosclerosis , 23 : 451 , 1976 . 50 . Garbarsch , C . ,
Matthiessen ...

Author: Geoffrey Austin Gresham

Publisher: Charles C Thomas Pub Limited

ISBN:

Category: Medical

Page: 111

View: 977


Atherosclerosis

Contents Reitsma , W . D . Introduction I . Arntzenius , A . C . Environmental
factors in the development of atherosclerosis . . . . . . . II . Van Aken , W . G . Blood
coagulation , thrombosis and atherosclerosis . . . . . . III . Meinders , A . E . Type
114 ...

Author: W. D. Reitsma

Publisher:

ISBN:

Category: Arteriosclerosis

Page: 246

View: 170


Medical Management of Atherosclerosis

Containing over 1000 bibliographic citations, tables, and drawings, Medical Management of Atherosclerosis is an important resource for cardiologists, cardiothoracic surgeons, internists, family practice and primary care physicians, and ...

Author: John C. LaRosa

Publisher: CRC Press

ISBN: 9780824701499

Category: Medical

Page: 352

View: 468

This state-of-the-art reference discusses nonsurgical treatment to prevent, arrest, or reverse the progression of atherosclerosis-outlining specific methods to reduce coronary risk factors, including hypercholesterolemia, cigarette smoking, hypertension, hyperinsulinemia, and hypoestrogenemia. Suggests that medical approaches may be more effective than bypass surgery or angioplasty in managing coronary artery disease! Presenting atherosclerosis as a diffuse, nonisolated disease that cannot be adequately treated by focusing on individual lesions, Medical Management of Atherosclerosis analyzes the effect of gonadal hormones, especially estrogens, on the process of atherosclerosis describes pharmacological interventions combined with blood pressure lowering, lipid reduction, and hormone therapies furnishes guidelines for bringing atherosclerosis prevention regimens into clinical practice addresses the cost effectiveness of atherosclerosis intervention examines the potential of genetics and gene therapy in treating atherosclerosis and much more! Containing over 1000 bibliographic citations, tables, and drawings, Medical Management of Atherosclerosis is an important resource for cardiologists, cardiothoracic surgeons, internists, family practice and primary care physicians, and interns, residents, fellows, and medical school students in these disciplines.

Atherosclerosis

Atherosclerosis is a chronic inflammatory disease that affects medium and large-sized arteries.

Author: Slavica Mitrovska

Publisher: Nova Biomedical Books

ISBN: 9781606926772

Category: Atherosclerosis

Page: 26

View: 929

Atherosclerosis is a chronic inflammatory disease that affects medium and large-sized arteries. It begins after birth and the progression depends on several factors - traditional triad: hypertension, hyperlipidemia and diabetes mellitus, then age, sex, smoking and sedentary life-style. At the beginning atherosclerosis is asymptomatic and we cannot estimate appropriately its frequency, but its complications - coronary artery diseases, cerebrovascular diseases, peripheral arterial diseases, which occur late, are responsible for more than half of the yearly mortality in the world. Unfortunately, sudden cardiac death may be the first clinical manifestation. The incipient event is endothelial dysfunction, as a result of injury, caused by high level of cholesterol [especially w-density-lipoprotein LDL], hyperglycemia, hypertension, smoking, infectious agents, and toxins. Endothelial cells overexpress adhesion molecules - vascular cell adhesion molecule-1 [VCAM-1] and increases recruitment of inflammatory cells - monocytes [Mo], T-cells and subsequent release of monocyte chemo-attractant protein-1 [MCP-1] that results in additional leucocytes recruitment. Injured endothelium allows migration of inflammatory cells that release cytokines and lipids into the intima. That leads to cytokine-mediated progression of atherosclerosis and oxidation of LDL. Macrophages [MP] take up oxi-LDL and form foam-cell. They have metabolic activity and produce cytokines, proliferation of smooth muscle cells and formulate athero-fibrose plaque. Atherosclerotic plaque is composed of superficial layer - fibrose cap and lipid core, that consists of foam cells, extracellular lipid and necrotic cellular debris. It progresses as a result of accumulation of lipid and proliferation of smooth muscle cells and results in luminal narrowing of the arteries which leads to compromised blood and oxygen supply to the tissues. The gradually growing atherosclerotic plaques have thick fibrose cap and are stable. They cause symptoms of stable angina. Rapidly growing plaques cause unstable coronary artery disease. These plaques are mainly composed of lipids and have tiny fibrose cap that is prone to fissuring or rupture. Intraplaque hemorrhage from microvessels in plaque initiate platelet adhesion and activation of coagulation cascade that leads to platelet thrombus formation, i.e. promote thrombogenesis. Knowledge of the pathogenesis of the atherothrombosis modifies the diagnostic and therapeutic approach. Conclusion: Attention should be focused on the management of three points: 1. Endothelial dysfunction [correction of modified risk factors: hypertension, hyperlipidemia, diabetes mellitus, life-style-smoking, physical activity and food], 2. Atherosclerosis [modification of the inflammatory cascade, i.e. elimination of inflammatory pathways and inhibition of oxidation of LDL], 3. Thrombogenesis [inhibition of platelet adhesion, activation and aggregation].

Atherosclerosis

Fine structure of spontaneous atherosclerosis: the human lesion In any attempt to
understand the pathogenetic mechanisms operating in atherosclerosis, the study
of spontaneous lesions appears to be essential for determining the ...

Author: Gotthard Schettler

Publisher:

ISBN:

Category: Arteriosclerosis

Page: 1029

View: 926


Enzyme Biochemistry of the Arterial Wall as Related to Atherosclerosis

Artery - cont . pentose phosphate pathway in , 13 Arylsulphatase , 64 assay
methods , 64 biological significance , 64 distribution , 64 in human arteries , 64 in
human atherosclerosis , 64 Aspartate aminotransferase , 57 assay methods , 57 ...

Author: Tibor Zemplényi

Publisher:

ISBN:

Category: Arteriosclerosis

Page: 273

View: 994


Natural Hist of Coronary Atherosclerosis

Ziats , N . P . and Robertson , L . A . , Effects of peripheral blood monocytes on
human vascular cell proliferation , Atherosclerosis , 38 , 401 , 1981 . 320 . Joris , I
. , Stetz , E . , and Majno , G . , Lymphocytes and monocytes in the aortic intima .

Author: Constantin Velican

Publisher: CRC PressI Llc

ISBN:

Category: Medical

Page: 426

View: 260


Atherosclerosis and Its Origin

sion it is not possible to offer many data directly relating the diet to
atherosclerosis itself . Unfortunately , it is not now possible to evaluate directly ,
let alone to measure , atherosclerosis in life , so recourse is therefore made to the
reverse ...

Author: Maurice Sandler

Publisher:

ISBN:

Category: Arteriosclerosis

Page: 570

View: 642


The Glycation Hypothesis of Atherosclerosis

Morphologically , diabetic macroangiopathy is no different from arteriosclerosis
which occurs in nondiabetics ( Fig . 7.2B ) . Arteriosclerosis is a non -
inflammatory disease of arterial vessel walls which manifests as atherosclerosis (
affecting ...

Author: Camilo A. L. S. Colaco

Publisher: Landes Bioscience

ISBN: 9780412114915

Category: Medical

Page: 219

View: 680