Lung Imaging and Computer Aided Diagnosis

Lung cancer remains the leading cause of cancer-related deaths worldwide. Early diagnosis can improve the effectiveness of treatment and increase a patient's chances of survival.

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 1439845581

Category: Medical

Page: 496

View: 563

Lung cancer remains the leading cause of cancer-related deaths worldwide. Early diagnosis can improve the effectiveness of treatment and increase a patient’s chances of survival. Thus, there is an urgent need for new technology to diagnose small, malignant lung nodules early as well as large nodules located away from large diameter airways because the current technology—namely, needle biopsy and bronchoscopy—fail to diagnose those cases. However, the analysis of small, indeterminate lung masses is fraught with many technical difficulties. Often patients must be followed for years with serial CT scans in order to establish a diagnosis, but inter-scan variability, slice selection artifacts, differences in degree of inspiration, and scan angles can make comparing serial scans unreliable. Lung Imaging and Computer Aided Diagnosis brings together researchers in pulmonary image analysis to present state-of-the-art image processing techniques for detecting and diagnosing lung cancer at an early stage. The book addresses variables and discrepancies in scans and proposes ways of evaluating small lung masses more consistently to allow for more accurate measurement of growth rates and analysis of shape and appearance of the detected lung nodules. Dealing with all aspects of image analysis of the data, this book examines: Lung segmentation Nodule segmentation Vessels segmentation Airways segmentation Lung registration Detection of lung nodules Diagnosis of detected lung nodules Shape and appearance analysis of lung nodules Contributors also explore the effective use of these methodologies for diagnosis and therapy in clinical applications. Arguably the first book of its kind to address and evaluate image-based diagnostic approaches for the early diagnosis of lung cancer, Lung Imaging and Computer Aided Diagnosis constitutes a valuable resource for biomedical engineers, researchers, and clinicians in lung disease imaging.

Lung Imaging and CADx

This book overviews the current state-of-the-art techniques that have been developed to implement each of these CAD processing steps.

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 0429508905

Category: Technology & Engineering

Page: 384

View: 970

Developing an effective computer-aided diagnosis (CAD) system for lung cancer is of great clinical importance and can significantly increase the patient's chance for survival. For this reason, CAD systems for lung cancer have been investigated in a large number of research studies. A typical CAD system for lung cancer diagnosis is composed of four main processing steps: segmentation of the lung fields, detection of nodules inside the lung fields, segmentation of the detected nodules, and diagnosis of the nodules as benign or malignant. This book overviews the current state-of-the-art techniques that have been developed to implement each of these CAD processing steps. Overviews the latest state-of-the-art diagnostic CAD systems for lung cancer imaging and diagnosis Offers detailed coverage of 3D and 4D image segmentation Illustrates unique fully automated detection systems coupled with 4D Computed Tomography (CT) Written by authors who are world-class researchers in the biomedical imaging sciences Includes extensive references at the end of each chapter to enhance further study Ayman El-Baz is a professor, university scholar, and chair of the Bioengineering Department at the University of Louisville, Louisville, Kentucky. He earned his bachelor’s and master’s degrees in electrical engineering in 1997 and 2001, respectively. He earned his doctoral degree in electrical engineering from the University of Louisville in 2006. In 2009, he was named a Coulter Fellow for his contributions to the field of biomedical translational research. He has 17 years of hands-on experience in the fields of bio-imaging modeling and noninvasive computer-assisted diagnosis systems. He has authored or coauthored more than 500 technical articles (132 journals, 23 books, 57 book chapters, 211 refereed-conference papers, 137 abstracts, and 27 U.S. patents and disclosures). Jasjit S. Suri is an innovator, scientist, a visionary, an industrialist, and an internationally known world leader in biomedical engineering. He has spent over 25 years in the field of biomedical engineering/devices and its management. He received his doctorate from the University of Washington, Seattle, and his business management sciences degree from Weatherhead School of Management, Case Western Reserve University, Cleveland, Ohio. He was awarded the President’s Gold Medal in 1980 and named a Fellow of the American Institute of Medical and Biological Engineering for his outstanding contributions in 2004. In 2018, he was awarded the Marquis Life Time Achievement Award for his outstanding contributions and dedication to medical imaging and its management.

Computer Aided Detection and Diagnosis in Medical Imaging

Filling this need, Computer-Aided Detection and Diagnosis in Medical Imaging covers the major technical advances and methodologies s

Author: Qiang Li

Publisher: Taylor & Francis

ISBN: 1439871779

Category: Medical

Page: 454

View: 529

Improve the Accurate Detection and Diagnosis of Cancer and Other Diseases Despite the expansion of the CAD field in recent decades, there is currently no single book dedicated to the development and use of CAD systems. Filling this need, Computer-Aided Detection and Diagnosis in Medical Imaging covers the major technical advances and methodologies shaping the development and clinical utility of CAD systems in breast imaging, chest imaging, abdominal imaging, and other emerging applications. After a historical overview of CAD, the book is divided into four sections. The first section presents CAD technologies in breast imaging, which is the most advanced area of CAD application. The second section discusses CAD technologies in chest and abdominal imaging. The third section explores emerging CAD technologies in a wide range of imaging modalities designed to address a variety of diseases. The final section describes the current use of CAD systems in clinical practice as well as how CAD will play an important role in quantitative image biomarkers and imaging genomics research. This book brings together existing and emerging CAD approaches at a level understandable to students, CAD system developers, basic scientists, and physician scientists. Newcomers to CAD research will learn about fundamental aspects in the process of CAD system development. Developers of CAD systems will gain insight on designing new or improved CAD systems. Experienced researchers will get up-to-date information on the latest CAD technologies.

Computer aided Diagnosis in Medical Imaging

The development of CAD has now reached a new phase, since the first commercial unit of detection of breast lesion in mammograms was approved in June 1998 by the FDA for marketing and sale for clinical use.This book, Computer-Aided Diagnosis ...

Author: Kunio Doi

Publisher: Excerpta Medica

ISBN:

Category: Medical

Page: 563

View: 296

Hardbound. Over the last decade or so, many investigators have carried out basic studies and clinical applications toward the development of modern computerized schemes for detection and characterization of lesions in radiologic images, based on computer vision and artificial intelligence. These methods and techniques are generally called computer-aided diagnosis (CAD) schemes. The development of CAD has now reached a new phase, since the first commercial unit of detection of breast lesion in mammograms was approved in June 1998 by the FDA for marketing and sale for clinical use.This book, Computer-Aided Diagnosis in Medical Imaging, presents papers from the First International Workshop on Computer-Aided Diagnosis held on September, 1998 at the University of Chicago Downtown Center. The meeting provided a forum for leading researchers and practitioners in this rapidly expanding field, encompassing automated image analysis, quantitation of im

Level Set Method in Medical Imaging Segmentation

Lung Imaging and Computer Aided Diagnosis 10 (2011) 221–238. El-Baz, A., Gimel'farb, G., Abou El-Ghar, M., Falk, R.: Appearance-based diagnostic system for early assessment of malignant lung nodules.

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 1351373021

Category: Medical

Page: 396

View: 954

Level set methods are numerical techniques which offer remarkably powerful tools for understanding, analyzing, and computing interface motion in a host of settings. When used for medical imaging analysis and segmentation, the function assigns a label to each pixel or voxel and optimality is defined based on desired imaging properties. This often includes a detection step to extract specific objects via segmentation. This allows for the segmentation and analysis problem to be formulated and solved in a principled way based on well-established mathematical theories. Level set method is a great tool for modeling time varying medical images and enhancement of numerical computations.

Big Data in Multimodal Medical Imaging

... “A novel level set-based computer-aided detection system for automatic detection of lung nodules in low dose chest computed tomography scans,” in A. El-Baz and J. Suri, eds. Lung Imaging and Computer Aided Diagnosis, Chapter 10.

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 1351380729

Category: Computers

Page: 341

View: 769

There is an urgent need to develop and integrate new statistical, mathematical, visualization, and computational models with the ability to analyze Big Data in order to retrieve useful information to aid clinicians in accurately diagnosing and treating patients. The main focus of this book is to review and summarize state-of-the-art big data and deep learning approaches to analyze and integrate multiple data types for the creation of a decision matrix to aid clinicians in the early diagnosis and identification of high risk patients for human diseases and disorders. Leading researchers will contribute original research book chapters analyzing efforts to solve these important problems.

Cardiovascular Imaging and Image Analysis

Lung Imaging and Computer Aided Diagnosis 10 (2011) 221–238. 87. El-Baz, A., Gimel'farb, G., Abou El-Ghar, M., Falk, R.: Appearance-based diagnostic system for early assessment of malignant lung nodules.

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 0429806221

Category: Medical

Page: 436

View: 373

This book covers the state-of-the-art approaches for automated non-invasive systems for early cardiovascular disease diagnosis. It includes several prominent imaging modalities such as MRI, CT, and PET technologies. There is a special emphasis placed on automated imaging analysis techniques, which are important to biomedical imaging analysis of the cardiovascular system. Novel 4D based approach is a unique characteristic of this product. This is a comprehensive multi-contributed reference work that will detail the latest developments in spatial, temporal, and functional cardiac imaging. The main aim of this book is to help advance scientific research within the broad field of early detection of cardiovascular disease. This book focuses on major trends and challenges in this area, and it presents work aimed to identify new techniques and their use in biomedical image analysis. Key Features: Includes state-of-the art 4D cardiac image analysis Explores the aspect of automated segmentation of cardiac CT and MR images utilizing both 3D and 4D techniques Provides a novel procedure for improving full-cardiac strain estimation in 3D image appearance characteristics Includes extensive references at the end of each chapter to enhance further study

Prostate Cancer Imaging

El-Baz, A., Farag, A., Gimelfarb, G., Falk, R., El-Ghar, M.A. A novel level set-based computer-aided detection system for automatic detection of lung nodules in low dose chest computed tomography scans. Lung Imaging Comput. Aided Diagno ...

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 0429784678

Category: Technology & Engineering

Page: 376

View: 837

This book covers novel strategies and state of the art approaches for automated non-invasive systems for early prostate cancer diagnosis. Prostate cancer is the most frequently diagnosed malignancy after skin cancer and the second leading cause of cancer related male deaths in the USA after lung cancer. However, early detection of prostate cancer increases chances of patients’ survival. Generally, The CAD systems analyze the prostate images in three steps: (i) prostate segmentation; (ii) Prostate description or feature extraction; and (iii) classification of the prostate status. Explores all of the latest research and developments in state-of-the art imaging of the prostate from world class experts. Contains a comprehensive overview of 2D/3D Shape Modeling for MRI data. Presents a detailed examination of automated segmentation of the prostate in 3D imaging. Examines Computer-Aided-Diagnosis through automated techniques. There will be extensive references at the end of each chapter to enhance further study.

Lung Imaging and CADx

Computer-aided classification of lung nodules on computed tomography images via deep learning technique. OncoTargets Ther. 2015;8:2015–2022. 18. Suzuki K. Computer-aided detection of lung cancer. In Image-Based Computer-Assisted ...

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 042950828X

Category: Technology & Engineering

Page: 384

View: 299

Developing an effective computer-aided diagnosis (CAD) system for lung cancer is of great clinical importance and can significantly increase the patient's chance for survival. For this reason, CAD systems for lung cancer have been investigated in a large number of research studies. A typical CAD system for lung cancer diagnosis is composed of four main processing steps: segmentation of the lung fields, detection of nodules inside the lung fields, segmentation of the detected nodules, and diagnosis of the nodules as benign or malignant. This book overviews the current state-of-the-art techniques that have been developed to implement each of these CAD processing steps. Overviews the latest state-of-the-art diagnostic CAD systems for lung cancer imaging and diagnosis Offers detailed coverage of 3D and 4D image segmentation Illustrates unique fully automated detection systems coupled with 4D Computed Tomography (CT) Written by authors who are world-class researchers in the biomedical imaging sciences Includes extensive references at the end of each chapter to enhance further study Ayman El-Baz is a professor, university scholar, and chair of the Bioengineering Department at the University of Louisville, Louisville, Kentucky. He earned his bachelor’s and master’s degrees in electrical engineering in 1997 and 2001, respectively. He earned his doctoral degree in electrical engineering from the University of Louisville in 2006. In 2009, he was named a Coulter Fellow for his contributions to the field of biomedical translational research. He has 17 years of hands-on experience in the fields of bio-imaging modeling and noninvasive computer-assisted diagnosis systems. He has authored or coauthored more than 500 technical articles (132 journals, 23 books, 57 book chapters, 211 refereed-conference papers, 137 abstracts, and 27 U.S. patents and disclosures). Jasjit S. Suri is an innovator, scientist, a visionary, an industrialist, and an internationally known world leader in biomedical engineering. He has spent over 25 years in the field of biomedical engineering/devices and its management. He received his doctorate from the University of Washington, Seattle, and his business management sciences degree from Weatherhead School of Management, Case Western Reserve University, Cleveland, Ohio. He was awarded the President’s Gold Medal in 1980 and named a Fellow of the American Institute of Medical and Biological Engineering for his outstanding contributions in 2004. In 2018, he was awarded the Marquis Life Time Achievement Award for his outstanding contributions and dedication to medical imaging and its management.

Stochastic Modeling for Medical Image Analysis

A novel level setbased computer-aided detection system for automatic detection of lung nodules in low dose chest computed tomography scans. International Journal of Biomedical Imaging, 10:221–238, 2011. A. El-Baz, A. A. Farag, ...

Author: Ayman El-Baz

Publisher: CRC Press

ISBN: 1466599081

Category: Medical

Page: 284

View: 972

Stochastic Modeling for Medical Image Analysis provides a brief introduction to medical imaging, stochastic modeling, and model-guided image analysis. Today, image-guided computer-assisted diagnostics (CAD) faces two basic challenging problems. The first is the computationally feasible and accurate modeling of images from different modalities to obtain clinically useful information. The second is the accurate and fast inferring of meaningful and clinically valid CAD decisions and/or predictions on the basis of model-guided image analysis. To help address this, this book details original stochastic appearance and shape models with computationally feasible and efficient learning techniques for improving the performance of object detection, segmentation, alignment, and analysis in a number of important CAD applications. The book demonstrates accurate descriptions of visual appearances and shapes of the goal objects and their background to help solve a number of important and challenging CAD problems. The models focus on the first-order marginals of pixel/voxel-wise signals and second- or higher-order Markov-Gibbs random fields of these signals and/or labels of regions supporting the goal objects in the lattice. This valuable resource presents the latest state of the art in stochastic modeling for medical image analysis while incorporating fully tested experimental results throughout.